Sunday 26 January 2014

Top 10 Most Painful Medical Conditions

Most Painful Medical Conditions

10. Shingles (Herpes Zoster)

Shingles is caused by the varicella-zoster virus, the same virus that causes the chickenpox. According to the Mayo Clinic, “After you’ve had chickenpox, the virus lies inactive near your spinal cord and brain.” After several years the virus may become active again, causing a painful abdominal rash in the form of a single row of blisters.


Although shingles is not life-threatening, it’s certainly not enjoyable. The condition cause up to 5 weeks of pain and itchy, open sores.


Shingles is transferrable via direct contact with the open blisters, but only to people who are susceptible to the varicella-zoster virus. There is a vaccination if you choose to accept the risks, but it wears off.

9. Tetanus

Tetanus is caused by the bacteria Clostridium tetani, spores of which are generally found in soil around the world. The bacteria can enter the body through an open wound. Once infection has begun, the bacteria create a poison called tetanospasmin.


This nasty poison is the reason tetanus makes it on the top 10 most painful diseases list. The poison attacks the body by blocking nerve communications between the central nervous system and the muscles.


The nerve block causes spasms that typically begin in the jaw muscles, causing lockjaw. They then travel to the feet and hands, chest, neck, and abdominal muscles, and finally landing in the back.


These spasms can be so severe that they strain the muscles into tearing. Back spasms can be so violent that the spinal cord fractures.


Like shingles, tetanus can also be prevented by vaccination if you choose to accept the risks. And again, the vaccine only lasts for awhile.

8. Pancreatitis

Pancreatitis is the inflammation of the pancreas ”“ a small gland behind the stomach responsible for producing digestive enzymes and insulin. The condition may be acute or chronic.


Inflammation is caused when the enzymes produced in the pancreas become active inside the pancreas, rather than in the small intestine where they’re supposed to be activated. The enzymes then begin to eat away at the tissue of the pancreas, rather than the food in the small intestine.


An estimated 70% of pancreatitis cases in the United States are caused by excessive alcohol consumption. Others are genetic and some have an unknown cause.

7. Frozen Shoulder (Adhesive Capsulitis)

Frozen shoulder is caused by inflammation in the joint capsule, which prevents the shoulder bones from moving.


What’s worse, however, is the vicious circle the inflammation causes. You don’t want to move your arm because of the pain. With decreased motion comes increased stiffness. Increased stiffness causes even less motion. Eventually, the joint becomes so painfully inflamed you can’t move it at all.

6. Fibromyalgia

The cause of this debilitating condition is unknown, despite how common it has become. Symptoms include chronic, body-wide pain, most especially in the soft tissues such as the muscles, tendons and joints. It affects primarily women between age 20 and 50.

5. Kidney Stones

Kidney stones are most commonly caused by dehydration. The kidneys’ primary purposes are to separate waste toxins from the blood and flush them from the body via the urinary tract.



Fail to take in enough liquids and the toxins can easily build up and create sharp crystals. These crystals then stack up on each other to create stones.
A variety of kidney stones exist, however, and may come from other sources such as chemotherapy, gout in men, or a urinary tract infection in women.

4. Lesch-Nyhan Disease

This rare condition is characterized by excessive uric acid caused by the body’s inability to process purines, a naturally occurring substance in all the body’s cells.


Excessive uric acid causes gout-like symptoms, including painful swelling of the joints, kidney and bladder stones, and other unusual symptoms like self-destructive behavior and strange body motions.


This is a genetically inherited syndrome and occurs mostly in young boys. Lesch-Nyhan sufferers may have to be restrained to reduce self-destructive behavior. They frequently require a wheelchair to get around.

3. Dercum Disease (Adiposis Dolorosa)

Dercum disease is a rare condition primarily found in postmenopausal, obese women. According to Dr. Marjan Yousefi of the Geisinger Medical Center, “The pain is out of proportion to the physical findings and is often described as ”˜all fat hurts.’” The pain appears to be caused by multiple fatty deposits that compress body-wide nerves. It is widespread and chronic pain that worsens with increased fatty tissue and hormonal cycles.

2. Ebola Hemorrhagic Fever

This terrible infection is caused by one of the five strains of the Ebola virus. Its onset is sudden and causes fever, body and joint aches in the first few days. These symptoms are followed by diarrhea, vomiting, stomach pain, and internal and external bleeding.
Outbreaks of Ebola are sporadic, but the condition is extremely painful. Some patients are able to recover but many affected succumb to this disease.

1. Cluster Headaches

Cluster headaches are considered by many to be the worst pain a human can feel. This condition, also called “suicide headaches,” is characterized by sudden onsets of excruciating pain in or around the eyes or on one side of the head.


The pain occurs in cyclical patterns or “clusters,” hence the name. The period may last for weeks or even months, followed by sessions of remission in which no headaches occur. Cycles may be predictable, in that they occur during the same period every year.


Cluster headaches differ from migraines in that sufferers “usually avoid lying down during an attack, because this position seems to increase the pain.” The pain does not linger like a migraine either. Sufferers report the pain leaves almost as soon as it happens, but leaves them completely exhausted.

Source: Faculty of Medicine

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